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First Target Batch(Batch01) of Target Selection focused on three Gram-negative bacterial genera: Burkholderia, Brucella and RickettsiaWe used a modification of the standard bioinformatics pipeline to identify potential drug targets within these organisms; and selected 196 targets with similarity to sequences in the DrugBank database of know drug targets, as well as 13 orthologues of ftsZ. For a detailed report of the bioinformatic filters used and the targets selected click here. You can access a spreadsheet listing all 209 targets by clicking on the thumbnail below. For a key to link Target IDs to Organism, please see the table here. |
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