Participating Institutions

The SSGCID includes the following research organizations: Seattle Children's Research Institute, University of Kansas, Dartmouth College, Washington University in St. Louis, the University of Washington, and Washington State University.

This partnership represents a unique blending of academic, institutional, and industrial efforts with a history of producing technological advances and innovations, expertise in infectious diseases and drug development, and proven ability to work with challenging protein targets, employing state-of-the-art structural genomic research.

Click on the logos below for more information about each site.

SCRI is responsible for the overall management for the SSGCID structure determination effort as well as protein purifications from bacterial expression and mammalian systems as well as cloning, expression and purification of protein-protein complexes.

WSU provides equipment and expertise for NMR-based determination of the structures of a small number of proteins that cannot be solved by X-ray crystallography.

The University of Kansas (KU) provides crystallization screening and production, pre-screening of crystals before they are sent for data collection at the synchrotron beam lines, and structure determination for the SSGCID.

Washington University in St. Louis provides functional characterization of proteins, training, and education of students in structural biology.

The UW PPG provides high-throughput cloning and testing of target proteins in bacterial expression vectors, as well as large-scale protein production and purification.

The UW NMR provides equipment and expertise for NMR-based determination of the structures of a small number of proteins that cannot be solved by X-ray crystallography.

The UW CryoEM provides structure determination via CryoEM.

The UW IPD provides modeling of structures and development of modeling software.

Dartmouth College provides functional characterization of proteins and training, and education of students in structural biology.