Seattle Structural Genomics Center for Infectious Disease

Other Mentions

Crystal Structure of Methyonil-tRNA Synthetase from Rickettsia typhi in Complex with its Cognate Aminoacid
Penteado RF, Iulek J. Biochimie 219 (April 2024) 63-73.   PMID:37673171.

Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus
Fata F, Gencheva R, Cheng Q, Lullo R, Ardini M, Silvestri I, Gabriele F, Ippoliti R, Bulman CA, Sakanari JA, Williams DL, Arner ESJ, Angelucci F. Redox Biol (2022). May (51)   PMID:35276442.   PMCID:PMC8914392.

Structural and biophysical characterization of the Burkholderia pseudomallei IspF inhibitor L-tryptophan hydroxamate
Blain JM, Grote D, Watkins S, Goshu GM, Muller C, Gorman J, Ranieri G, Walter R, Hofstetter H, Horn JR, Hagen TJ. Bioorg. Med. Chem. Lett. (2021). 48 (128473)   PMID:34298132.   PMCID:PMC8407143.

Engineered SAM Synthetases for Enzymatic Generation of AdoMet Analogs with Photocaging Groups and Reversible DNA Modification in Cascade Reactions
Michailidou F, Klocker N, Cornelissen NV, Singh RK, Peters A, Ovcharenko A, Kummel D, Rentmeister A. Angew. Chem. Int. Ed. Engl. (2021). 60 (1)   PMID:33017502.   PMCID:PMC7839696.

Biochemical characterization of phosphoserine phosphatase SerB2 from Mycobacterium marinum
Pierson E, Wouters J. Biochem. Biophys. Res. Commun. (2020). 530 (4) 739-744.   PMID:32782143.

Identification and Repurposing of Trisubstituted Harmine Derivatives as Novel Inhibitors of Mycobacterium tuberculosis Phosphoserine Phosphatase
Pierson E, Haufroid M, Gosain TP, Chopra P, Singh R, Wouters J. Molecules 25 (2)   PMID:31963843.   PMCID:PMC7024313.

Structure of a critical metabolic enzyme: S-adenosylmethionine synthetase from Cryptosporidium parvum
Ohren J, Parungao GG, Viola RE. Acta Crystallogr F Struct Biol Commun (2019). 75 (Pt 4) 290-298.   PMID:30950830.   PMCID:PMC6450524.

A novel series of enoyl reductase inhibitors targeting the ESKAPE pathogens, Staphylococcus aureus and Acinetobacter baumannii
Kwon J, Mistry T, Ren J, Johnson ME, Mehboob S. Bioorg. Med. Chem. (2018). 26 (1) 65-76.   PMID:29162308.   PMCID:PMC5733704.

Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase
Santa Maria JPJr, Park Y, Yang L, Murgolo N, Altman MD, Zuck P, Adam G, Chamberlin C, Saradjian P, Dandliker P, Boshoff HIM, Barry CE3rd, Garlisi C, Olsen DB, Young K, Glick M, Nickbarg E, Kutchukian PS. ACS Chem. Biol. (2017). 12 (9) 2448-2456.   PMID:28806050.   PMCID:PMC6298432.

Nano-yeast-scFv probes on screen-printed gold electrodes for detection of Entamoeba histolytica antigens in a biological matrix
Grewal YS, Shiddiky MJA, Spadafora LJ, Cangelosi GA, Trau M. Biosens Bioelectron (2013). 55 417-422.   PMID:24434498.
  -- translational notes :

Structural guidance for malaria and TB
Lou KJ. Science-Business eXchange (2013).

Publishing structural genomics results continued: the SSGCID Special Issue
Weiss MS, Einspahr H. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. (2011). 67 (Pt 10) 1159.   PMID:21045283.   PMCID:PMC3212352.

User-loaded SlipChip for equipment-free multiplexed nanoliter-scale experiments
Li L, Du W, Ismagilov R. J. Am. Chem. Soc. (2009). 132 (1) 106-11.   PMID:20000708.   PMCID:PMC2802657.

Multiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods
Li L, Du W, Ismagilov RF. J. Am. Chem. Soc. (2009). 132 (1) 112-9.   PMID:20000709.   PMCID:PMC2805062.

Phospholipid-binding protein EhC2A mediates calcium-dependent translocation of transcription factor URE3-BP to the plasma membrane of Entamoeba histolytica
Moreno H, Linford AS, Gilchrist CA, Petri WA. Eukaryotic Cell (2009). 9 (5) 695-704.   PMID:20023071.   PMCID:PMC2863961.

Novel inhibitors of Rickettsia prowazekii methionine aminopeptidase from the Malaria Box
Chen C, Sharma I, Daraji D, Horn JR, Hagen TJ. Bioorg. Med. Chem. Lett. (2023). 87 (May 1) 129281.   PMID:37031729.

Novel starting points for fragment-based drug design against mycobacterial thioredoxin reductase identified using crystallographic fragment screening
Fusser F, Wollenhaupt J, Weiss MS, Kummel D, Koch O. Acta Crystallogr. D Biol. Crystallogr. (2023). 79 (Sep 1) 857-865.   PMID:37574972.   PMCID:PMC10478635.