NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease

FUN_01

Functional Study 1: Use structure-based inhibitor design to assess the function of bacterial immunophilins as potential targets for broad-spectrum antibiotic discovery.

Project lead: Darren Begley, UCB
Project collaborators: Mitali Sarkar-Tyson, University of Western Australia, Australia; Isobel Norville, Dominic Jenner, DSTL, UK; Nicholas Harmer, University of Exeter, UK; Ulrike Holzgrabe, University of Würzburg, Germany
Status: Project completed

Link to Final Report

Link to Original Proposal


Summary of Progress

Cumulative status by number of Unique Targets

*to date

Featured Structures

Overlay of 3 Bartonella BID domains

Bartonella BID


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