Seattle Structural Genomics Center for Infectious Disease


The primary mission of SSGCID and our sister center CSBID is to determine the 3D atomic structures of proteins and other molecules with an important biological role in human pathogens themselves, or molecules involved in host-pathogen interactions, by applying state-of-the art high-throughput (HTP) technologies and methodologies. Pathogens include those on the NIAID Category A-C agents as well as emerging and re-emerging infectious disease organisms, each year for a period of five years. This program will also support research projects that utilize experimental approaches to better characterize the molecular mechanisms of protein targets and gain further insight into the functional roles of these targets.

view of PDB structure 6n1c

Inorganic pyrophosphatase from Legionella pneumophila.

Structure solved and published by students advised by Krystle Mclaughlin
in collaboration with SSGCID, highlighted by the journal editor.

Organisms studied




Overview of results

Total structures 1717
Unique targets 1182
Protein-ligand complexes 877
Selection by the scientific community Targets Structures
Direct request 8497 635
Nominated from SSGCID selection 2207 387

Publish our structures

We are looking for authors to drive publication of any of our structures.
Want to be first/last author? You can!

Participating institutions

Seattle Children's University of Washington Kansas University Washington State University Washington University in St. Louis Dartmouth College